Pallidotomy is an ablative procedure that involves the creation of a small lesion in the globus pallidus or pallidum, a sub-region in the chain of nuclei called the basal ganglia necessary for the control of movement. Historically, pallidotomy offered relief to Parkinson’s patients but had been associated with physical and cognitive side effects. The use of pallidotomy has largely been replaced by DBS although may be recommended in selected cases where DBS is contraindicated.