Neuro-oncology expertise

Our skilled neurosurgeons use their subspecialized training and 20-plus years of experience to deliver exceptional care to hundreds of patients each year. Performing more complex neuro-oncology procedures than any other practice in the region, we ensure that you receive the most advanced care possible. We participate in an array of clinical trials so our patients have access to the most advanced treatments available.

Our Neuro-Oncology and Skull-base Surgery Center Experts

We bring together the best medical minds to care for you

Dr. Kaptain of New Jersey Brain and Spine, neuro-oncology expert and neurosurgeon.

George J. Kaptain, MD

Kangmin Daniel Lee, MD

Dr. Rotoli is one of the most highly trained surgeons in the US for neurosurgical oncology and the radiosurgical treatment of tumors.

Giorgio J. Rotoli, DO

In addition to our skilled neurosurgeons, we work with other top neuro-oncology specialists that may include radiation oncologists, medical neuro-oncologists, neuroradiologists, neurologists and others. Together, this interdisciplinary team carefully reviews your history and test results to jointly recommend optimal treatments and minimize your number of physician visits. We communicate quickly and often with this network of professionals to ensure you receive coordinated, timely and effective care.

Hear more from the
Neuro-Oncology team

We recommend the treatment option that will provide the best result with the least risk.

- Kangmin Daniel Lee, MD

Conditions and Treatments

We make sure you understand your condition and treatment options

Being diagnosed with a brain tumor is hard. That’s why we take the time to fully explain your condition and treatment options, treating you with empathy and understanding throughout your individualized care journey. While we can perform the most intricate, complex procedures, we always start by considering the most conservative treatment appropriate for your situation—reserving surgery only for when it’s the best option.

Common Conditions

We treat a wide variety of neuro-oncology conditions

Each of our neuro-oncology surgeons is solely dedicated to caring for patients with brain, spine and skull-base tumors, enabling them to treat you with unparalleled experience and expertise.

Metastatic brain tumors
Metastatic spine tumors
Glioblastoma
Astrocytoma
Oligodendroglioma
Meningioma
Pituitary adenoma
Acoustic neuroma

Full list of conditions

Common Treatments

We perform a wide variety of neuro-oncology treatments

We offer a wide range of the most advanced procedures available to treat your tumor, including:

Gamma knife radiosurgery
Microvascular decompression
Cortical mapping and ‘awake’ brain surgery
Craniotomy for brain tumor
Transphenoidal pituitary surgery

Full list of treatments

Clinical Trials

Neuro-Oncology Clinical Trials

Newly Diagnosed High Grade Glioma

A Phase III Clinical Trial Evaluating DCVax®-L, Autologous Dendritic Cells Pulsed With Tumor Lysate Antigen for the Treatment of Glioblastoma Multiforme (GBM)
A Prospective, Multi-center Trial of NovoTTF-100A Together With Temozolomide Compared to Temozolomide Alone in Patients With Newly Diagnosed GBM
An International, Randomized, Double-Blind, Controlled Study of Rindopepimut/GM-CSF With Adjuvant Temozolomide in Patients With Newly Diagnosed, Surgically Resected, EGFRvIII-positive Glioblastoma
Open-label, Randomized, Controlled, Phase 3 Safety and Efficacy Study of Trans Sodium Crocetinate (TSC) with Radiation Therapy and Temozolomide in Newly Diagnosed Glioblastoma (GBM) Biopsy-Only Subjects
Pilot Study of NovoTTF in Conjunction with Temozolomide Chemoradiation for Newly Diagnosed Glioblastoma
A Phase II/III Randomized Trial of Veliparib or Placebo in Combination With Adjuvant Temozolomide in Newly Diagnosed Glioblastoma With MGMT Promoter Hypermethylation
A Randomized Phase 2 Single Blind Study of Temozolomide plus Radiation Therapy combined with Nivolumab or Placebo in Newly Diagnosed Adult Subjects with MGMT-Methylated (tumor O6 methylguanine DNA methyltransferase) Glioblastoma

Recurrent High Grade Glioma

A Phase II Study of Rindopepimut/GM-CSF in Patients With Relapsed EGFRvIII-Positive Glioblastoma
A Phase 1 Ascending Dose Trial of the Safety and Tolerability of Toca 511 in Patients With Recurrent High Grade Glioma
Phase 2 Dose-Escalation Study of TPI 287 in Combination With Bevacizumab in Adults With Recurrent Glioblastoma
A Phase II Randomized Trial Comparing the Efficacy of Heat Shock Protein-Peptide Complex-96 (HSPPC-96)
A Phase II, Multicenter, Open-Label, Single Arm Study to Evaluate the Safety, Tolerability, and Efficacy of Disulfiram and Copper Gluconate in Recurrent Glioblastoma
A Randomized, Multicenter, Phase 2 Study of DSP-7888 Dosing Emulsion in Combination With Bevacizumab Versus Bevacizumab Alone in Patients With Recurrent or Progressive Glioblastoma Following Initial Therapy
A Phase 2/3 Randomized, Open-Label Study of Toca 511, a Retroviral Replicating Vector, Combined With Toca FC versus Standard of Care in Subjects Undergoing Planned Resection for Recurrent Glioblastoma or Anaplastic Astrocytoma
Expanded Access (Compassionate Use) Treatment Protocol: Rindopepimut (CDX-110)